Kugwiritsa ntchito hydroxypropyl methylcellulose mu malonda opangira mankhwala

HyPromellose (hpmc) ndi cellulose yotupa yomwe yagwiritsidwa ntchito kwambiri m'makampani opanga mankhwala chifukwa cha ntchito zake zabwino komanso zopanda pake. Madera ake ofunsira amaphatikiza piritsi, samva zinthu, zophatikiza, othandizira - omasulidwa, ndikukonzekera mankhwala amadzimadzi ndi ma gels.

1.

Pakupanga za piriki, hpmc monga chomangira zitha kukulitsa mphamvu yomanga mankhwala, kumawathandiza kuti ipange mapiritsi okhazikika nthawi yothetsera. HPMC Maners ali ndi zotsatirazi:
Mphamvu yamakina: ma network a viscous opangidwa ndi hpmc mu piritsi amathandizira kukonza mphamvu ya piritsi ndikuchepetsa chiopsezo cha kuphatikizika kwa kachilomboka.
Sinthani Umodzi: Chifukwa cha kusungunuka Kwake Kwabwino m'madzi, hpmc imatha kugawidwa moyenera pamwamba pa tinthu tating'onoting'ono tomwe timagwiritsira ntchito mankhwalawa patebulo lililonse.
Kukhazikika: HPMC imawonetsa kukhazikika kwabwino pansi pa kutentha kosiyana ndi chinyezi, ndipo imatha kukhalabe ndi ma piritsi pomwe ophatikizidwa ndi zachilengedwe.

2. Zosokoneza

Ntchito ya kusamvana ndikupanga mapiritsi omwe amasankhidwa mwachangu atalumikizana ndi madzi kuti amasule zosakaniza za mankhwala. HPMC imatha kulimbikitsa kuti piri lipangidwe bwino chifukwa cha kutupa kwake:
Kutupa kwa hydration: Pamene hpmc imakumana ndi madzi, imayamwa mwachangu madzi ndi kutupa, ndikupangitsa piritsi kuti lituluke, motero kumasula mankhwalawa.
Kusintha Nthawi Yosasinthika: Posintha mamasukidwe a HPMC, nthawi yopanda tanthauzo la mapiritsi imatha kulamuliridwa molondola kuti akwaniritse zomwe zimamasulidwa ndi mankhwala osiyanasiyana.

3. Zipangizo zophatikizika

HPMC imachita mbali yofunika kwambiri patebulo. Kutha kwake kwa mawonekedwe abwinobwino ndikuteteza mankhwala kumapangitsa kuti ikhale chinthu chophatikiza:
Zotsatira zake: Kulankhulana kwa HPMC kumatha kudzipatula kumayiko ogwiritsira ntchito piritsi kuchokera kudera lakunja kuti ateteze dealiquecence, maxidations ndi zithunzi.
Kuwongolera Maonekedwe: Kulankhulana kwa HPMC kumatha kupereka malo osalala kunja, kukonza mawonekedwe ndi kumeza komeza mapiritsi.
Kusintha Kutulutsa kwa Mankhwala: Kutengera mawonekedwe osiyanasiyana a hpmc ndi makulidwe okutira, kumasulidwa kapena kumasulidwa komwe kumatheka.

4. Omwe amathandizidwa - omasulidwa

HPMC imagwiritsidwa ntchito kwambiri pakukonzekera kokhazikika. Kudzera mu chotchinga cha gel osakaniza, kumatha kuchedwetsa kugwiritsa ntchito mankhwalawa ndikupeza chithandizo cha nthawi yayitali:
Chotchinga gel: M'matchulidwe am'madzi, hpmc chimasungunuka ndikupanga gels gels sviel, yomwe imatha kuyendetsa mamasulidwe a mankhwalawa.
Kutulutsa kokhazikika: Makulidwe a Kuzungulira ndi Kukhazikika kwa HPMC imatha kulamulidwa ndendende kuti mukwaniritse mankhwala okhazikika komanso olongosoka.
Mankhwala ochepetsedwa bwino: Mafomu osula kusungidwa amatha kuchepetsa kuchuluka kwa mankhwalawa kwa odwala ndikuwongolera kutsatana ndi kugwira ntchito kwa mankhwala osokoneza bongo.

5. Madzi Kukonzekera ndi Ma gels

HPMC imachita mbali yofunika kwambiri monga chitsirizidwe ndi kusungunula m'madzi kukonzekera ndi ma gels:
Kukula Kwakukulu: HPMC imapanga yankho la collomlonel m'madzi, lomwe limatha kuwonjezera mafayilo amadzi kukonzekera ndikusintha kuyimitsidwa.
Kukhazikika: HPMC imatha kusunga mamasukidwe okhazikika pansi pa pH, zomwe zimathandizira kukhazikitsa mankhwala osokoneza bongo komanso kupewa.

6. Ntchito zina

Hpmc
Kukonzekera kwa ophthalmic: HPMC imagwiritsidwa ntchito ngati mafuta mu misozi ndi madontho amaso kuti athetse zizindikiro zowuma.
Kukonzekera kwa Nasil: Monga Thicker mu mphuno, hpmc imatha kupitiriza nthawi yosunga mankhwala mu nkal carch.
Kukonzekera kwapakhungu: hpmc amatha kupanga filimu yoteteza pokonzekera pakhungu kuti athandize mankhwala opezeka pakhungu.

Monga ntchito yosangalatsa, hydroxypropyl methylcellulose imagwiritsidwa ntchito kwambiri m'makampani opanga mankhwala. Ntchito zake zingapo zopangidwa ndi piritsi, zokutira, kutukuka, kutukuka - kukonzekera kwamadzi ndi ma gels kumapangitsa chidwi ndi kukonzekera kwa mankhwala. HPMC yakhala chinthu chofunikira komanso chofunikira m'makampani opangira mankhwala chifukwa cha zinthu zake zabwino za biocacompompompor. M'tsogolomu, poyambitsa kusinthasintha kwaukadaulo wamankhwala, chiyembekezo chogwiritsa ntchito cha HPMC mu kafukufuku wa mankhwala ndi chitukuko ndi kapangidwe ka kapangidwe kake chikhala chowonjezera.