Kodi HPMC imakhudza bwanji ma vicy?

Hydroxypropyl methylcellulose (hpmc) ndi polymer polymer yomwe imagwiritsidwa ntchito m'mafakitale, mankhwala ndi chakudya. Chimodzi mwazinthu zazikulu za HPMC mu zinthu zosiyanasiyana ndikusintha ma viscence, omwe amakwaniritsidwa kudzera mwa ma molecular mawonekedwe ndi kuyanjana ndi ma sol sols (nthawi zambiri madzi).

1. Mapangidwe a HPMC ndi momwe amapangidwira
HPMC imakhala ndi msana wa celluulose ndi methoxy ndi hydroxypyl oyimira. Maunyolo ake a cellulose amatenga magulu ambiri a hydroxyl (-Oh), omwe amatha kupanga zomangira za hydrogen ndi mamolekyulu amadzi, potero amalimbikitsa mafayilo a yankho. Hydroxypyll ndi methoxy m'malo mwa HPMC Molekyulu imakhudzanso ubale wake ndikusandulika ndi madzi. M'madzi, unyolo wa HPMC Molecular unyolo umatha kuchitika ndikumwa madzi ambiri, potero akuwonjezera ufa wa yankho.

Mitundu Yosiyanasiyana ya HPMC iwonetsa mawonekedwe osiyanasiyana chifukwa cha madigiri awo osiyanasiyana a memoxy ndi hydroxypropyl. Nthawi zambiri, olankhula ndi ma hydroxypropyl amagwira bwino ntchito, pomwe HPMC yokhala ndi methoxy yokwera kwambiri imasiyana ndi kuchuluka kwa thupi komanso kukoma kutentha. Chifukwa chake, kapangidwe ka HPMC imakhudza kwambiri mafayilo ake.

2. Makhalidwe osungunuka ndi mafayilo a HPMC
HPMC ili ndi madzi abwino osungunuka, omwe amathandizira kuwonjezera mafakisoni m'matumba am'madzi. Madzi, unyolo wa HPMC amatenga madzi ndikupanga mawonekedwe ochulukirapo, zomwe zimapangitsa kuchepa kwa madzimadzi a yankho komanso kuchuluka kwa mafayilo. Kukhumudwitsa kumeneku ndi njira yodutsamo, komanso kutentha ndi p pH imakhudza. Nthawi zambiri, hpmc zimasungunuka mwachangu pamitenthedwe yochepa, koma maonedwe ake amawonjezeka ndi kutentha kwambiri. Chifukwa chake, zochulukitsa kusinthika kutentha malinga ndi mitundu ina, mawidwe opambana.

Kusungunuka kwa HPMC kumagwirizananso ndi mtengo wa pH. Osalowerera ndale mpaka alkaline mitundu, hpmc imasungunuka bwino ndikuwonjezera mafayilo; Mukakhala pansi pa acid acidic kapena alkalinines, solubility ndi mawonekedwe a HPMC yaletsa. Chifukwa chake, mu zinthu zosiyanasiyana, kusinthika kwa ma viscc ku HPMC kumafunikiranso kuganizira za mtengo wa sing'anga.

3. Zotsatira za HPMC ndende pa mafayilo
Kuchuluka kwa hpmc ndi imodzi mwazinthu zazikulu zomwe zikukhudza mafayilo. Pamene kuchuluka kwa HPMC kumawonjezeka, matchulidwe a maselo a maselo omwe amapangidwa mu yankho amakhala wowoneka bwino ndipo ma utoto amawonjezeka kwambiri. Kukhazikika kochepa, kulumikizana pakati pa zilonda za HPMC molecular ndi zofowoka, ndipo mafayilo sasintha kwambiri. Komabe, pamene HPMC idafika pamlingo winawake, kulumikizana ndi kugwirizanitsa pakati pa ma unyolo kumapangitsa kuti ma vinyo azikula bwino.

Kuyesera kumawonetsa kuti kuchuluka kwa HPMC kuli mkati mwa mtundu wina, mafakisi ake amachulukana molingana mwachindunji ndi kuchuluka kwa ndende. Komabe, pamene kuchuluka kwazinthu zili zazitali kwambiri, zomwe zimapangitsa kuti zitheke zizisintha, kuwonetsa pseudoplastity kapena thixotropy, ndipo ma visc amachepetsa ndi kuchuluka kwa chimbudzi. Chifukwa chake, mu mapulogalamu othandiza, kuchuluka kwa HPMC yowonjezeredwa kulamulidwa molingana ndi zofunikira kuti mukwaniritse mawonekedwe abwino.

4..
Kulemera kwa HPMC ndikofunikira kuti mudziwe mafayilo ake. Nthawi zambiri, zokulirapo kulemera kwa HPMC, mafayilo owonjezera yankho lake. Izi ndichifukwa choti HPMC yokhala ndi kulemera kwakukulu kumatha kukhala ma unyolo otalikirana ndi ma network ochulukirapo, potengera madzi abwino a yankho ndikuwonjezera mamasukidwe. Chifukwa chake, HPMC yokhala ndi zolemera zosiyanasiyana za ma molecular zitha kugwiritsidwa ntchito kusintha zinthu zina za zinthu zosiyanasiyana.

M'mapulogalamu ena, kusankha zolemera zapamwamba HPMC kumatha kusintha zochulukitsa za chinthucho, monga chotsirizira pomanga zida; Pomwe mukugwiritsa ntchito, monga gawo la mankhwala opangira mankhwala, ocheperako otsika hpmc angafunike kusankhidwa kuti asankhe kumasulidwa kwa mankhwalawa kapena kukonza kukoma.

5. Zotsatira za kutentha pakukweza kwa HPMC
Makutu a HPMC amasintha kwambiri ndi kutentha. Nthawi zambiri, mafano a HPMC yankho la HPMC amatsika kutentha kwambiri. Izi ndichifukwa kutentha kwakukulu kumawononga maonda a hydrojeni pakati pa mamolekyulu a HPMC ndikuchepetsa kuchuluka kwa unyolo, potero kuchepetsa ufawo. Komabe, m'malo ena apadera, mawonekedwe a HPMC amatha kuwonjezeka mkati mwa kutentha kwina, komwe kumakhala kogwirizana kwambiri ndi mawonekedwe ake osokoneza bongo.

Pa kutentha kochepa, mawonekedwe a hpmc yankho la HPMC ndilokwera ndipo kuyenda kwa unyolo kumaletsedwa. Katunduyu amapangitsa kuchita bwino ntchito komwe kumakutuwa kwa chinthucho pamatenthedwe otsika amafunika kuwonjezeka.

6. Mphamvu ya Shear Pakutuluka kwa HPMC
Mayankho a HPMC nthawi zambiri amawonetsa kuwononga misozi, ndiye kuti, ma viskeni amachepetsa kukula. Pamitengo yotsika ya Shear, kapangidwe ka HPMC molecular unyolo wamtunduwu ndi wathunthu, zomwe zimalepheretsa madziwo yankho, potengera mawonekedwe apamwamba. Komabe, kuchuluka kwa mikwingwirima yayitali, kukopeka ndi kuphatikizika kwa maunyolo ma unyolo amawonongeka, ndipo ma virucy amachepetsa. Katunduyu amagwiritsidwa ntchito kwambiri m'makampani monga momwe akulimbikitsira, utoto ndi zokutira, ndipo amatha kusintha mwayi wopanga zinthu pomanga.

7. Zotsatira zakuchokera kunja
Pa ntchito zambiri, hpmc nthawi zambiri zimagwiritsidwa ntchito limodzi ndi zina zowonjezera. Mitundu Yosiyanasiyana yazowonjezera, monga mchere, ogwiritsa ntchito ndi ma poizoni ena, zimakhudza mafayilo a HPMC. Mwachitsanzo, zowonjezera mchere zimachepetsa mawisa a HPMC chifukwa ma ions amchere a HPMC Molecular ndikuwononga macheza a hydrogen omwe amapanga. Otsatsa ena amatha kugwira ntchito synergilly ndi hpmc kuti muwonjezere mawonekedwe a yankho la yankho.

Monga momwe amagwiritsidwira ntchito kwambiri, mphamvu ya HPMC pa Iscycy yogulitsa imatheka makamaka chifukwa chophatikizika ndi kapangidwe kake, kupsa mtima, kulemera kwakunja monga kutentha, kuchuluka kwakunja monga kutentha. Mwakusintha moyenera magawo awa a HPMC, kolondola kwa kuwongolera kwa ma viruyo kumatha kuchitika kuti akwaniritse zosowa za mapulogalamu osiyanasiyana.