Momwe hpmc imathandizira kukonza matope a matope ndi pulasitala

Hydroxypropyll methylcellulose (hpmc) ndi cellulose yopanda ionic eyelil eyelil ogwiritsidwa ntchito kwambiri pakumanga, makamaka matope ndi pulasitala. Monga owonjezera, hpmc imatha kusintha zinthu zosiyanasiyana za zinthuzi, kuphatikizapo kugwirira ntchito, kusungidwa kwamadzi, kukana, etc.

1. Mankhwala ndi kapangidwe ka HPMC

HPMC ndi polymer polymer yomwe idapangidwa ndikusintha magulu a hydroxyl a cellulose ndi hydroxypropropropropropropropropropropropy. Chipinda chake choyambirira ndi glucose, chomwe chimalumikizidwa ndi β-1,4-glycosiidic. Cellulose yayitali imapereka mawonekedwe abwino opanga mafilimu komanso zomata, pomwe kukhazikitsa kwa methyl ndi hydroxypyl kumathandiza kususuka ndikukhazikika.

Kapangidwe ka mankhwala kwa HPMC kumaperekanso izi:

Kusungunuka kwamadzi: imatha kusungunuka mwachangu m'madzi ozizira kuti apange madzi owoneka bwino.

Kusintha kwa Viscty: Njira yothetsera HPMC ili ndi ma visct yosinthika, yomwe imatengera kulemera kwake komanso kudekha.

Kukhazikika: Kukhazikika kwa acids ndi zitsulo ndipo kumatha kupitiliza kugwira ntchito pazinthu zosiyanasiyana.

2. Makina a HPMC kuti musinthe matope a matope ndi pulasitala

(2.1). Sinthani kusungidwa kwamadzi
Kusungidwa kwamadzi kumatanthauza kuthekera kwa matope kapena pulasitala kuti asunge madzi, omwe ndi ofunikira kwambiri hydrate hydration ndi kuuma. HPMC imasintha madzi pogwiritsa ntchito njira zotsatirazi:

Mphamvu yopanga filimu: HPMC imapanga filimu yopyapyala mu matope kapena pulasitala, ndikuchepetsa malire a madzi.
Mafuta a Madzi a Mafuta: mamolekyu a HPMC amatha kuyamwa madzi ambiri, kuchepetsa kuchepa kwamadzi pomanga.
Kusungidwa kwamphamvu kwamadzi kumathandiza kuti muchepetse bwino simenti yokwanira, potero kumawonjezera mphamvu ndi kulumikizana kwa matope ndi pulasitala. Kuphatikiza apo, zimachepetsanso mapangidwe a ming'alu yoyambitsidwa ndi kutayika kwamadzi kwambiri.

(2.2). Sinthani Kuthana
Kugwira ntchito kumatanthauza kugwirira ntchito kwa matope ndi pulasitala pa njira yomanga, monga madzi ndi kugwirira ntchito. Njira zomwe HPMC imathandizira kugwirira ntchito:

Kuwongolera Mapukiti: HPMC imapereka mphamvu bwino, ndikupereka zosakaniza mapiko ndi madzi.
Kupewa Kuletsedwa ndi Kusankha: zotsatira za kukula kwa HPMC zimathandizanso kufalitsa ngakhale kufalitsa tinthu tambiri, kupewa kuchepetsedwa kapena kusankhana matope kapena pulasitala.
Izi zimapangitsa matope kapena kupha pulasitala kuti azigwira ntchito pomanga, kulola kuti mwinanso kugwiritsidwa ntchito komanso kuwumba, kuchepetsa mwayi wa kutaya zinyalala ndikugwirira ntchito.

(2.3). Kuchulukitsa kukana
Matope ndi pulasitala amatha kuswa chifukwa cha kuchuluka kwa shringnage nthawi yolimbana, ndipo HPMC imathandizira kuchepetsa izi:

Kusinthasintha: Kapangidwe ka netiweki yopangidwa ndi HPMC m'matope kumawonjezera kusinthika kwa matope ndi pulasitala, potero kumapangitsa komanso kutsanzitsa nkhawa.
Kuuma yunifolomu: chifukwa HPMC imapereka madzi abwino osungira madzi, madzi amatha kumasulidwa motero, kuchepetsa kusintha kwa voliyumu pouma.
Izi zimapangitsa kuthekera kwa mapangidwe opanga ndikusintha kukhazikika kwa nkhaniyi.

3. Zitsanzo za ntchito za HPMC mu matope ndi pulasitala

(3.1). Tile zomatira
Pa tile zomata, hpmc imapereka madzi osungira ndi anti-slint, kulola matailesi kuti atsatire mpaka kukakhala ndi ntchito yabwino yomanga.

(3.2). Matope okhaokha
Matope okhathamira pamafunika madzi ambiri komanso kudziletsa. Kusunga kwamadzi kwamphamvu kwa HPMC ndi kusinthika kwa ma vina kumathandizira kukwaniritsa izi, zomwe zimapangitsa kuti pakhale bwino.

(3.3). Pulasitala
HPMC imawonjezera chotsatsa ndi kupindika pokana pulasitala, makamaka mu khoma la khoma, ndipo mutha kuthana ndi kusokonekera ndikuwonongeka chifukwa cha zinthu zosiyanasiyana zachilengedwe.

4. Kukwaniritsa kugwiritsa ntchito HPMC

(4.1). Kugwiritsa ntchito
Kuchuluka kwa HPMC yomwe imagwiritsidwa ntchito mu matope ndi pulasitala nthawi zambiri imakhala yochepa kwambiri pankhani ya kuchuluka, monga 0,1% mpaka 0,5%. HPMC yochuluka kwambiri imapangitsa kuti mamasukidwe ochulukirapo komanso kukhudza kugwirira ntchito; Zochepa kwambiri zimapangitsa kuti zikhale zovuta kusintha kwambiri magwiridwe antchito.

(4.2). Kugwirizana ndi zina zowonjezera
Mukamagwiritsa ntchito HPMC, ndikofunikira kuti muzigwirizana ndi zowonjezera zina zamankhwala (monga momwe amapangira madzi, okonda mpweya, etc.) Kuonetsetsa kuti palibe vuto lazomwe zakhudzidwa.

Monga zowonjezera zamankhwala zowonjezera, kugwiritsa ntchito HPMC mu matope ndi pulasitala kwambiri bwino kusungidwa kwake, kugwirira ntchito komanso kusokonekera. Kusintha kumeneku sikungowonjezera mphamvu yomanga ndi mtundu wa zinthu zakuthupi, komanso kusintha kulimba komanso kudalirika kwa polojekiti. Pazolinga zina, mwa kusintha moyenera Mlingo ndi gawo la HPMC, matope a matope ndi pulasitala amatha kukhazikika.