Kuphatikizika kwa HPMC / HPS Cold-kozizira

Hydroxypylrose filimu (HPMC) yazabwino kwambiri, koma chifukwa chakuti HPMC ndi yotsika kwambiri, yomwe siyikuyatsa kutentha pang'ono, zomwe zimapangitsa kuti pakhale mafilimu abwino; Kuphatikiza apo, mtengo wake waukulu umachepetsa ntchito. Hydroxypropyl starch (HPS) is a low-cost cold gel, its addition can increase the viscosity of HPMC at low temperature, improve the processing performance of HPMC, and reduce the production cost, further, the same hydrophilicity , glucose units and hydroxypropyl groups all contribute to improve the compatibility of these two polymers. Chifukwa chake, njira yotentha yozizira yotentha idakonzedwa ndikuphatikiza HPS ndiHpmc, ndipo zotsatira za kutentha pa gelc / hps Hot-ozizira-chimfine chozizira kwambiri chidaphunziridwa mwadongosolo pogwiritsa ntchito ma riedometer ndi maluso ang'onoang'ono omwazikana. , kuphatikizidwa ndi chizolowezi cha kutentha kwa kutentha pa microstraction ndi katundu wa nembanemba, kenako adapanga ubale womwe uli pakati pa kapangidwe kake ka kapangidwe kake kake kake kake kake kake pazinthu zamagetsi zotentha.

Zotsatirazi zikuwonetsa kuti pamtunda wapamwamba, gel yokhala ndi zolimba za HPMC ili ndi chikhalidwe chambiri komanso chofunikira chokhazikika, ndipo kukula kwa mitundu yotsika mtengo ndi yayikulu; Pa kutentha kochepa, zopezeka za HPS zapamwamba za gel zapamwamba za neel zimakhala ndi chikhalidwe chapamwamba, chotchuka chokhazikika chofanana, komanso mawonekedwe ofanana ndi odzipha okha. Kwa zitsanzo zomwe zili ndi chiwerengero chofananira, moddus komanso chofananira chofanana ndi kachulukidwe kakang'ono ka ma gels otentha kwambiri ndi okwera kuposa kutentha kochepa. Kutentha kowuma kumatha kusokoneza mawonekedwe a gel a gel asanayime, kenako kumakhudza kanema wa mazira, ndipo pamapeto pake ali ndi chofunikira kwambiri pa makina opanga mafilimuwo, ndikupangitsa kuti filimuyo ikhale yopanda kutentha kwambiri. Okwera kuposa kuuma pa kutentha kochepa. Mulingo wozizira ulibe zotsatira zodziwika bwino pa kachitidwe, koma kumathandizira kachulukidwe ka mufilimuyo. M'dongosolo lino, kuchuluka kwa filimuyi kumatha kukhudza makina a filimuyo. Ntchito zimakhudza kwambiri.

Kutengera ndi kukonza membrane, phunziroli linazindikira kuti kugwiritsa ntchito ayoonine kuti agwiritse ntchito vpmc / HPS ophatikizidwa ndi njira yolumikizira ndi ma microscope. Njira, yomwe ili ndi njira yogwiritsira ntchito njira yogwiritsira ntchito gawo la magawo gawo lokhala ndi chibwibwi. Pogwiritsa ntchito njira yatsopanoyi, kuphatikiza ndi mawonekedwe a sictradscopy, scanning elekitiropey, kusintha kwa magawo, kuyerekezera, komanso kusinthika, mawonekedwe, mawonekedwe a makanema amapangidwa. ubale pakati pa magwiridwe antchito. Zotsatira za microscope zowunikira zikuwonetsa kuti dongosololi likusintha gawo la HPS pomwe 50%, komanso zinthu zapakati pa 50% zikupezeka mufilimuyi, zomwe zikuwonetsa kuti dongosololi lili ndi lingaliro linalake; Kusanthula, mawonekedwe a thermagramvimetric ndi zotsatira za sem kumatsimikizira kuphatikiza. Dongosolo limakhala ndi gawo linalake. Modulus wa filimu yolumikizidwa ikasintha zinthu kwa HPS ndi 50%. Pamene zilonda za HPS ndizoposa 50%, mbali yolumikizirana ya zitsanzo zophatikizika zimachoka mzere wolunjika wolumikiza ma treles olumikizirana ndi 50%, imasochera kuchokera pamzere wowongoka. , omwe amayamba chifukwa cha kusintha kwa phazi.