Hydroxypropyl me cellulose HPMC, yomwe imadziwikanso kuti hydrox roluuse, ndi ma celluule to sollubose yoyera komanso madzi otentha celylose. Bungwe la hydroxypyl ndi methyl mulingo wa ether ndi mphete yazipatso zam'madzi zophatikizika, ndi mtundu wa ma cellulose osakaniza ether. Ndiko kupanga polymer, ma viscoelastic, ma visme ogwiritsidwa ntchito ngati mafuta mu ophthalmology, kapena ngati prophum kapena yodzaza ndi mankhwala am`kamwa.
1. Njira yopanga
Pulf zamkati ndi αcellulose zomwe 97%, chidwi cha 720ml / g ndi mafilimu a fiber a 2.6mm adanyowa mu 49% Naoh yankho la 40 ℃ kwa masekondi 50. Kenako zamkati zidatayidwa kuti zichotse zowonjezera 49% ya Naoh kuti apeze cellulose. Chiwerengero cha kulemera kwa (49% Naoh aquneous yankho) kuti (gawo lolimba la zamkati) poyerekeza ndi Naoh kulkali cellulose kukhala 1.49. Cellulose cellulose yomwe idapezeka (20kg) imayikidwa m'matumbo a Jactar rexiry, kenako nkutsuka ndikutsukidwa ndi nayitrogeni kuti muchotse mpweya wabwino wokwanira. Kenako, kutentha kwa riyakitala chidayang'aniridwa pa 60. pomwe kuchititsa kwamkati kunachitika.
Kenako 2.4kg DME adawonjezeredwa ndipo kutentha mu riyakitalayo adalamuliridwa mpaka 60 ℃. Pambuyo kuwonjezera kwa Dimethyl ether, methylene chloride adawonjezeredwa kuti apange chiyezo cha Moorylene Chloride ku Cellulose. Pambuyo powonjezera chlorometane ndi ma propylen oxide, kutentha kwa riyakitalayo adalamulidwa kuchokera ku 80 ℃ mpaka 90 ℃. Kuphatikiza apo, zomwe zimatenga kwa mphindi 20 pa 90 ℃.
Mafuta amachotsedwa mu riyakitalayo ndi mtundu wa hydroxypypyl methyl cellulose amachotsedwa kwa Articy. Kutentha kwa rode hydroxypypyl methyl cellulose inali 62 ℃. Yerekezerani kukula kwa tinthu tating'onoting'ono tomwe timapilira tinthu tambiri toyambitsa tinthu tating'onoting'ono togawa gawo la rade hydroxpyl centyl celluse, iliyonse imakhala ndi kukula koyambirira.
Zotsatira zake, kukula kwa tinthu tating'onoting'ono kwa tinthu tating'onoting'ono tinali 6.2mm. Omwe adapeza phono hydroxpyl methl cellulose adayambitsidwa munthawi yopumira (krc ntrader s1, l / phompho) pothamanga kwa 100rpm Zotsatira zofanana ndi zojambula zisanu pogwiritsa ntchito zojambula zisanu ndi zitsulo zosiyanasiyana, kukula kwa tinthu tating'onoting'ono tinali 1.4mm. Kuphatikiza madzi 80 ℃ madzi otentha kwa owola a romropyl a methyl celyilose mu thankiyo ndi kutentha kwa jekete. Kuchuluka kwa kuchuluka kwa kuchuluka kwa ma hydropypyl lydropyl celyl cellulose mpaka 0,1, ndipo osuta amapezeka. Kusungunuka kunasunthidwa nthawi yosalekeza 80 ℃ kwa mphindi 60.
Kenako, malo otsekemera amaperekedwa ku liwiro lozungulira la 0,5 rpm ndi pre-stated ratary resefer (zosefera)). Kutentha kwa grout ndi 93 ℃. Gwiritsani ntchito pampu kuti ipereke malo osalala, kupanikizika kampu ndi 0.2MPA. Kukula kotseguka kwa zosefera kuzungulira ndi 80μm, ndi malo osefera ndi 0.12M2. Kusungunuka komwe kunaperekedwa ku frese frequary kutengera kudzera mu fyuluta ndikusintha kukhala keke yosefera. Kutulutsa keke komwe kumachitika ndi 0.3mka yothilika ndi madzi otentha 95 ℃ kukhala ndi gawo lokwanira la 10,0 ku gawo lokhazikika la hydroxypropyl celylose, yomwe imasefedwa kudzera mu fyuluta.
Madzi otentha amaperekedwa kudzera pampu yotupa ya 0,5mka. Madzi otentha ataperekedwa, 0,3mka Thumu imaperekedwa. Kenako, mutatsuka zinthu zimachotsedwa pamtunda ndi starpiper ndikutuluka m'makina ochapira. Njira zoperekera slurry kuti muchotse zinthu zosambitsidwa zimachitika mosalekeza. Monga momwe zimayesedwa pogwiritsa ntchito kutentha - kuyanika kwa hygrometer, madzi omwe ali ndi matenda otsukidwawo adachotsedwapo anali 52.8%. Zinthu zotsukidwa zotulutsidwa kuchokera ku zosefera zovunda zozungulira zinali zowumitsa mpweya pa 80 ℃, ndi kuphwanyidwa mu mphero yopambana kuti ipeze hydroxypropyl celyolose.
2.amabustiwa
Zogulitsa za HPMC zimagwiritsidwa ntchito ngati thickener, wobalalitsa, binder, emulsifier ndi kukhazikika m'makampani ojambula. Amagwiritsidwanso ntchito kwambiri mu stores yopanda, sorochemical, ceramic, pepala, chikopa, mankhwala, chakudya, zodzoladzola ndi mafakitale ena.
Post Nthawi: Mar-23-2022