Kuweruza mtundu wa hydroxypropyl methyl cellulose

Hydroxypropyl me cellose (hpmc) ndi polimme yosiyanasiyana yomwe imapeza kugwiritsa ntchito kwambiri m'mafakitale osiyanasiyana, kuphatikizapo za mankhwala osokoneza bongo, kuphatikiza, chakudya, zodzola, zodzola. Mapulogalamu ake osiyanasiyana amachokera pamalo ake apadera, monga luso lopanga mafilimu, kukula kwa mphamvu, kumangiriza, ndi madzi osungira. Mtundu wa HPMC ndikofunikira kuti muwonetsetse kuti phindu ndi chitetezo chazinthu zomwe zimagwiritsidwa ntchito.

Upangiri wa 1.Chemical:
Kupanga kwamankhwala kwa HPMC ndikofunikira kwambiri. HPMC imachokera ku cellulose, kusinthidwa kudzera mu hydroxypropropylation ndi methylation njira. Mulingo wa zolowa m'malo mwa hydroxypyl ndi methoxy magulu amakhudza mawonekedwe ake. Mfundo zapamwamba za DS DS nthawi zambiri zimayambitsa kusungunuka kwamadzi ndikuchepa kutentha kwamphamvu. Njira zowunikira monga magilear a nyukiliya (NMR) Spestroscopy ndi infrared (IR) Spectroscopy imagwiritsidwa ntchito (IR) imagwiritsidwa ntchito pofuna kudziwa zomwe zimapangidwa ndi zitsanzo za HPMC.

2.Put:
Kuyera ndi gawo lofunikira kwambiri la mtundu wa HPMC. Zosayera zimatha kukhudza magwiridwe antchito ndi kukhazikika kwa zinthu. Zinyalala zodziwika zimaphatikizapo zotsalira, zitsulo zolemera, ndi zodetsa zodetsa nkhawa. Njira zingapo zowunikira monga ma gramatography (hplc), gasi), komanso mozama plasma-misa mozama.

3.Maleclar kulemera:
Kulemera kwa HPMC kumakopa nyama yake yazachinyengo, kusungunuka, komanso luso la makanema. HPMC yapamwamba kwambiri imawonetsa mafayilo ambiri ndi mphamvu yamafilimu. Gel Permear Chromatography (GPC) ndi njira yogwiritsidwa ntchito kwambiri yodziwitsa kuchuluka kwa madeti a HPMC.

4.Choni:
Makulidwe akuyenera kuphatikiza kofunikira kwa HPMC kukhala yabwino kwa HPMC, makamaka pamapulogalamu monga mankhwala opanga mankhwala, komwe kumachitika ngati wothandizira kukula. Maonekedwe a mayankho a HPMC amakhudzidwa ndi zomwe zimakhudzidwa ndi zinthu monga chidwi, kutentha, ndi mtengo wake. Njira zosiyanasiyana masomnescoms, kuphatikizapo zopota za machecheke ndi capillary maso, amagwiritsidwa ntchito kuyeza mafayilo a HPMC pamikhalidwe zosiyanasiyana.

5.P ndi chinyezi:
The PH ndi chinyezi cha HPMC imatha kusintha kukhazikika kwake komanso kuphatikizidwa ndi zosakaniza zina zopanga. Zolemba chinyezi ndizofunikira makamaka ngati chinyezi chambiri chimatha kuyambitsa kukula komanso kuwonongeka kwa HPMC. Kuuzidwa kwa Karl Fischer nthawi zambiri kumagwiritsidwa ntchito kudziwa chinyezi, pomwe v metters amagwiritsidwa ntchito poyeza pH.

6. Kukula kukula ndi Morphology:
Kukula kwa tinthu ndi morphology kusewera gawo lofunikira mu kayendedwe ka HPMC ufa wa HPMC. Njira monga laser yosiyanasiyana ndi scanning ma microctopy (Sem) amagwiritsidwa ntchito kuti azindikire tinthu tating'onoting'ono ndi morphology ya marfc tinthu tambiri.

7. Katundu 7.
Mafuta otenthetsera monga kutentha kwagalasi (TG) ndi kutentha kwa matenthedwe kumapereka chidziwitso mu kukhazikika ndi kukonza zinthu za HPMC. Kusambira kosiyanasiyana kwa calorimetry (DSC) ndi thermagravimetric Selecsis (TGA) nthawi zambiri amagwiritsidwa ntchito posanthula matenthedwe a HPMC.

8.Gulani ndi mawonekedwe a makanema:
Zofunsira zofunsira za gel kapena mapangidwe a filimu, kutentha kwa miyala ndi kapangidwe ka mafilimu ku HPMC ndikofunikira magawo. Miyeso ya Rheogical ndi mayeso opanga mafilimu amachitidwa kuti awone zinthu izi mogwirizana.

Kuwunika mtundu wa hydroxypropyl methy cellouse (hpmc) Njira zosiyanasiyana zowunikira zimagwiritsidwa ntchito kuwunikira magawo awa, kuonetsetsa kuti HPMC imakwaniritsa zofunikira pazomwe akufuna. Mwa kusunga miyezo yapamwamba kwambiri, opanga HPMC akhoza kuonetsetsa kuti, chitetezo, komanso magwiridwe antchito osiyanasiyana.